We are entering a new era of innovation. The basic technology that powered the digital revolution is nearing its theoretical limits and the most exciting opportunities lie in new technologies. Many of these will be rooted in the physical world, as we learn to use bits to transform atoms. Some investors are already beginning to make the shift to a new model. However, there is a growing trend of early seed investors who focus on mitigating specific areas of technical risk. They offer entrepreneurs more than capital, but also lab space, scientific expertise and business mentorship.