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Innovation Crossroads

Empowering Aspiring Hard-Tech Entrepreneurs

Starting new energy-related technology companies can be challenging, and that’s one reason the number of energy start-ups has declined significantly over the past decade. Innovation Crossroads, a Lab-Embedded Entrepreneurship Program, is supported by the US Department of Energy—including the Advanced Materials and Manufacturing Technologies Office, Building Technologies Office, Office of Electricity, and Office of Science’s Advanced Scientific Computing Research program and Basic Energy Sciences program—and by the Tennessee Valley Authority. The program leverages Oak Ridge National Laboratory’s (ORNL’s) unique scientific resources and capabilities and connects the nation’s top innovators with experts, mentors, and networks in technology-related fields to take world-changing ideas from R&D to the marketplace.

Innovation Crossroads is a two-year fellowship program that focuses on energy and advanced manufacturing technologies. Through an annual national call and competitive stage-gate process, top entrepreneurial-minded fellows are selected to join the program. Selected innovators receive a fellowship that includes a personal living stipend, a health insurance stipend, a travel allowance, a substantial grant to use on collaborative R&D at ORNL, and comprehensive mentoring assistance to build a sustainable business model.

By embedding the next generation of top technical talent within ORNL, Innovation Crossroads positions entrepreneurial researcher fellows to address fundamental energy and manufacturing challenges identified by industry.

Program Impacts

51

Start-ups supported

323

Jobs created

$307.4 million

In follow-on funding

22

Start-ups with sales

$34 million

In sales revenue

29

Patents granted

Featured News

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    Ascend Manufacturing closes seed round, lands major project with NNSA

    The founder Justin Nussbaum said Ascend was selected to work on a top-secret project with the National Nuclear Security Administration (NNSA) to manufacture small, complex parts. What if you could print thousands of complex parts in a single day, using materials no one else can? That’s the challenge Justin Nussbaum set out to solve. Several major issues plague

  • Group of six people standing on stage at 865 Fest 2025 holding an oversized check for $10,000 awarded to Witching Hour as the Judges’ Choice Prize Winner, presented by the Innov865 Alliance.

    Witching Hour Takes Home Top Prize at 865 Fest Startup Pitch Competition

    In the first-ever full-day 865 Fest, formerly known as Knoxville’s Startup Day, about 300 people gathered inside Bridgewater Place in West Knoxville. The day-long programming included conversations about the collaborative efforts on the Covenant Health Park stadium downtown, keynotes from Mark Pancratz and Jordan Harper, and breakout sessions on valuation, relational equity, and more. But

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